Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, though it’s likely a name that doesn’t quite ring a bell. This rare genetic disease affects the motor and sensory nerves in the arms and legs, leading to challenges with movement and sensation. CMT is caused by mutations in over 100 different genes, making it incredibly difficult for researchers to pinpoint exactly what’s going wrong in patients—and, more importantly, how we can stop it. I’ve explored a potential unifying mechanism behind this complexity and worked on developing models to better understand and eventually treat this disorder.